The so-called ion selective electrode developed in the late 1960s has actually gone through a hundred years of development. In the history of modern science, famous scientists such as Helmohotz, Giese, Habbe, Dole and HKonb-cknn, etc., have played an important role in its development.
The development of ion selective electrodes originated from glass electrodes. In 1875, hToms. Second, put two metal sheets into two electrolytic solutions respectively, and form a battery with a glass film in the middle, and measure the electromotive force of the battery. In 1881, Helmoholt Z [52] made a historic report at the Faraday Lecture, which also discussed in detail the properties of the Dagong II battery of the glass spherical membrane. In 1906, physiologist Cremer [13] first observed that when the pH of the aqueous solution in contact with glass changed, the potential across the membrane also changed. He added sodium hydroxide to the N solution of 0.6 μl, and found that the change of the glass membrane potential reached 306 millivolts. 3].
