This standard specifies a liquid chromatograph mass spectrometry method for the determination of tetrabromobisphenol A and phosphoric acid tris (1,3-dichloroisopropyl) ester in water-based paints and solar-based paints. It is suitable for the determination of these two compounds in these two coatings, and the lower limits for their determination are 1 mg/kg and 5 mg/kg, respectively. In the principle part, water-based paints are ultrasonic extraction with ethyl acetate, while solar-based paints are directly ultrasonic extraction with acetonitrile, and the extract is filtrated and then determined by liquid phase chromatograph mass spectrometry/mass spectrometry. Reagents and materials include standard substances and solutions such as ethyl acetate, acetonitrile, tetrabromobisphenol A, phosphoric acid tris (1,3-dichloroisopropyl) ester, and organic phase filtration membranes. Required instruments and equipment include liquid chromatograph mass spectrometer/Mass Spectrometer.